Gimble Lab - Recent Publications

Links to the Journal and PubMed are provided.  Viewing will depend on your institution's access to the journals involved.

2007

Zvonic S, Lefevre M, Kilroy G, Floyd ZE, Delany JP, Kheterpal I, Gravois A, Dow R, White A, Wu X, Gimble JM.  Secretome of primary cultures of human adipose-derived stem cells: modulation of serpins by adipogenesis.  Molecular & Cellular Proteomics 6:18-28, 2007.

Zvonic S, Floyd ZE, Mynatt RL, Gimble JM. Circadian Rhythms and the regulation of metabolic tissue function and energy homeostasis.  Obesity 15:539-543, 2007.

Zvonic S, Ptitsyn AA, Kilroy G, Wu X, Conrad SA, Scott LK, Guiliak F, Pelled G, Gazit D, Gimble JM.  Circadian oscillation of gene expression in murine calvarial bone.  Journal of Bone and Mineral Research 22:357-365, 2007.

Floyd ZE, Kilroy G, Wu X, Gimble JM.  Effects of prolyl hydroxylase inhibitors on adiopgenesis and hypoxia inducible factor 1 alpha levels under normoxic conditions.  Journal of Cellular Biochemistry, 2007. (Epub ahead of print)

2006

Guilak F, Lott KE, Awad HA, Cao Q, Hicok KC, Fermor B, Gimble JM.  Clonal analysis of the differentiation potential of human adipose derived adult stem cells.  Journal of Cellular Physiology 206:229-37, 2006.

Mitchell JB, Kevin McIntosh K, Zvonic S, Garrett S, Floyd ZE, Kloster A, Halvorsen YD, Storms RW, Goh B, Kilroy G, Wu X, Gimble JM. Immunophenotype of human adipose-derived cells: temporal changes in stromal-associated and stem cell-associated markers.  Stem Cells 24:376-385, 2006.

Ptitsyn AA, Zvonic S, Conrad SA, Scott LK, Mynatt RL, Gimble JM.  Circadian clocks are resounding in peripheral tissues.  PLoS Computational Biology 2:e16, 2006.

Zvonic S, Ptitsyn AA, Conrad SA, Scott LK, Floyd ZE, Kilroy G, Wu X, Goh BC, Mynatt RL, Gimble JM.  Characterization of peripheral circadian clocks in adipose tissues.  Diabetes 55:962-970, 2006.

Gimble JM, Zvonic S, Floyd ZE, Kassem M, Nuttall ME.  Playing with bone and fat.  Journal of Cellular Biochemistry 98:251-266, 2006.

Floyd ZE, Zvonic S, Nutall ME, Gimble JM.  Fine-Tuning Reception in the Bone: PPARgamma and Company.  PPAR Research 2006:52950 7 pages, 2006.

McIntosh K, Zvonic S, Garrett S, Mitchell JB, Floyd ZE, Hammill L, Kloster A, Halvorsen YD, Ting JP, Storms RW, Goh B, Kilroy G, Wu X, Gimble JM.  The immunogenicity of human adipose derived cells: Temporal changes in vitro.  Stem Cells 24:1246-53, 2006. 

Ptitsyn AA, Zvonic S, Gimble JM.  Permutation test for periodicity in short time series data. BMC Bioinformatics 7: Suppl 2:S10, 2006

Vidal MA, Kilroy GE, Johnson JR, Lopez MJ, Moore RM, Gimble JM.  Cell Growth Characteristics and Differentiation Frequency of Adherent Equine Bone Marrow–Derived Mesenchymal Stromal Cells: Adipogenic and Osteogenic Capacity.  Veterinary Surgery 35:601-610, 2006.

Izadpanah R, Trygg C, Patel B, Kriedt C, Dufour J, Gimble JM, Bunnell BA.  Biologic properties of mesenchymal stem cells derived from bone marrow and adipose tissue.  Journal of Cellular Biochemistry 99:1285-1297, 2006.

2005

Delany J, Floyd ZE, Zvonic S, Gravois A, Smith A, Reiners E, Wu X, Kilroy G, Lefevre M, Gimble JM.  Proteomic Analysis of Primary Cultures of Human Adipose Derived Stem Cells: Modulation by Adipogenesis.  Molecular and Cellular Proteomics 4:731-40, 2005.

Wang DW, Fermor B, Gimble JM, Awad HA, Guilak F.  The Influence of Oxygen on the Proliferation and Metabolism of Adipose Derived Adult Stem Cells.  Journal of Cellular Physiology 204:184-191, 2005.

Dubois S, Halvorsen Y-DC, Ravussin E, Gimble JM.  Primary Stromal Cell Culture from Adipose Tissue: From Liposuction to Needle Biopsy. Adipocytes 1:139-144, 2005.

No links available at this time

Thirumala S, Zvonic S, Floyd E, Gimble JM, Deivreddy RV. Effect of various freezing parameters on the immediate post-thaw membrane integrity of adipose tissue derived adult stem cells.  Biotechnology Progress 21:1511-1524, 2005.

Thirumala S, Gimble JM, Deivreddy RV.  Transport phenomena during freezing of adipose tissue derived adult stem (ADAS) cells.  Biotechnology and Bioengineering 92:372-83, 2005.

Devireddy RV, Thirumala S, Gimble JM.  Cellular response of adipose derived passage-4 adult stem cells to freezing stress. Journal of Biomechanical Engineering 127:1081-1086, 2005. 

Bogacka I, UkropecB, McNeil M, Gimble JM, Smith SR. Structural and functional consequences of mitochondrial biogenesis in human adipocytes in vitro. Journal of Clinical Endocrinology and Metabolism, 90:6650-6, 2005.

2004

Aust L, Devlin BH, Foster SJ, Halvorsen YDC, Hicok K, Kloster AL, du Laney TV, Sen A, Willingmyre D, Gimble JM.  Yield of Human Adipose Derived Adult Stem Cells from Liposuction Aspirates.  Cytotherapy 6:7-14, 2004.

Estes BT, Gimble JM, Guilak F. Mechanical signals as regulators of stem cell fate.  Current Topics in Developmental Biology 60:91-126, 2004.

Guilak F, Awad HA, Fermor B, Leddy HA, Gimble JM. Adipose-derived adult stem cells for cartilage tissue engineering.  Biorheology 41:389-399, 2004.

Gimble JM, Nutall ME.  Bone and fat: old questions, new insights.  Endocrine 23:183-188, 2004.

Nuttall ME, Gimble JM.  Controlling the balance between osteoblastogenesis and adipogenesis and the consequent therapeutic implications.  Current Opinion in Pharmacology 4:290-294, 2004.

Awad HA, Wickham MQ, Leddy  HA, Gimble  JM, Guilak F.  Chondrogenic Differentiation of Adipose-Derived Adult Stem Cells in Agarose, Alginate, or Gelatin Scaffolds. Biomaterials 25:3211-3222, 2004.  

Hicok K, du Laney T, Sheng Zhou Y, Halvorsen Y-DC, Hitt CD, Cooper LF, Gimble JM. Human Adipose Derived Adult Stem Cells Produce Osteoid In Vivo.  Tissue Engineering 10:371-380, 2004.

Safford, K. M., Safford, S. D., Gimble, J. M., Shetty, A. K., and Rice, H. E. Characterization of neuronal/glial differentiation of murine adult adipose-derived stromal cells. Experimental Neurology 187:319-28, 2004.

2003

Gimble J, Guilak, F.  Adipose-derived adult stem cells: isolation, characterization, and differentiation potential.  Cytotherapy 5:362-369, 2003.

Gimble JM, Guilak, F.  Differentiation potential of adipose derived adult stem (ADAS) cells. Current Topics in Developmental Biology 58:137-160, 2003.

Wickham QM, Erickson GR, Gimble JM, Vail TP, Guilak F. Multipotent Human Adult Stem Cells Derived from Infrapatellar Fat Pad of the Knee.  Clinical Orthopaedics and Related Research 412:196-212, 2003.

Gimble JM.  Adipose tissue-derived therapeutics.  Expert Opinion on Biological Therapy 3:705-713, 2003.

Awad H, Halvorsen Y-DC, Gimble JM, Guilak F.  Effects of TGF-β1 and Dexamethasone on Growth and Chondrogenic Differentiation of Adipose Derived Stromal Cells In Vitro.  Tissue Engineering, 9:1301-1312, 2003.