Cancer Prevention Laboratory

1. Leuschner, C., and Hansel, W. (2005) Targeting Breast and Prostate Cancers Through Their Hormone Receptors. Biol Reprod 73, 860-865

2. Leuschner, C., and Hansel, W. (2004) Membrane disrupting lytic peptides for cancer treatments. Curr Pharm Des 10, 2299-2310

3. Bodek, G., Kowalczyk, A., Waclawik, A., Huhtaniemi, I., and Ziecik, A. J. (2005) Targeted Ablation of Prostate Carcinoma Cells Through LH Receptor Using Hecate-CG{beta} Conjugate: Functional Characteristic and Molecular Mechanism of Cell Death Pathway. Exp Biol Med (Maywood) 230, 421-428

4. Leuschner, C., Enright, F. M., Melrose, P. A., and Hansel, W. (2001) Targeted destruction of androgen-sensitive and -insensitive prostate cancer cells and xenografts through luteinizing hormone receptors. Prostate 46, 116-125.

5. Hansel, W., Leuschner, C., Gawronska, B., and Enright, F. (2001) Targeted destruction of prostate cancer cells and xenografts by lytic peptide-beta LH conjugates. Reproductive Biology 1, 20-32

6. Leuschner, C., Enright, F., Gawronska, B., and Hansel, W. (2003) Membrane disrupting lytic peptide conjugates destroy hormone dependent and independent breast cancer cells in vitro and in vivo. Breast Cancer Research and Treatment 78s, 17-27

7. Bodek, G., Rahman, N. A., Zaleska, M., Soliymani, R., Lankinen, H., Hansel, W., Huhtaniemi, I., and Ziecik, A. J. (2003) A novel approach of targeted ablation of mammary carcinoma cells through luteinizing hormone receptors using Hecate-CGbeta conjugate. Breast Cancer Res Treat 79, 1-10

8. Zaleska, M., Waclawik, A., Bodek, G., Zezula-Szpyra, A., Li, X., Janowski, T., Hansel, W. H., Rahman, N. A., and Ziecik, A. J. (2004) Growth repression in diethylstilbestrol/dimethylbenz[a]anthracene-induced rat mammary gland tumor using Hecate-CGbeta conjugate. Exp Biol Med (Maywood) 229, 335-344

9. Gawronska, B., Leuschner, C., Enright, F. M., and Hansel, W. (2002) Effects of a lytic peptide conjugated to beta HCG on ovarian cancer: studies in vitro and in vivo. Gynecol Oncol 85, 45-52

10. Bodek, G., Vierre, S., Rivero-Muller, Huhtaniemi, I., Ziecik, A. J., and Rahman, N. A. (2005) A novel targeted therapy of Leydig and granulosa cell tumors through the luteinzing hormone receptor using a Hecate-chorionic gonadotropin beta conjugate in transgenic mice. Neoplasia 7, 497-508

11. Zaleska, M., Bodek, G., Jana, B., Hansel, W., and Ziecik, A. J. (2003) Targeted Destruction of Normal and Cancer Cells Through Lutropin/Choriogonadotropin Receptors Using Hecate-betaCG Conjugate. Exp Clin Endocrinol Diabetes 111, 146-153

12. Hansel, W., Leuschner, C. and Enright, F. (2006) Destruction of breast cancers and their metastases by lytic peptide conjugates in vitro and in vivo. Molecular and Cellular Endocrinology (In Press)

13. Bodek, G., Kowalczyk, A., Waclawik, A., Huhtaniemi, I., and Ziecik, A. J. (2005) Targeted Ablation of Prostate Carcinoma Cells Through LH Receptor Using Hecate-CG{beta} Conjugate: Functional Characteristic and Molecular Mechanism of Cell Death Pathway. Exp Biol Med (Maywood) 230, 421-428

14. Hansel, W., Leuschner, C. and Enright, F. (2006) Conjugates of lytic peptides and LHRH or βCG target and cause necrosis of prostate cancers and metastases. Molecular and Cellular Endocrinology 269, 26-33

15. Leuschner, C., Challa, S.S.R., Hansel, W., Soboyejo, W., Zhou, J. and Hormes, J. (2006) LHRH-conjugated magnetic iron oxide nanoparticles for detection of breast cancer metastases. Breast Cancer Research Treat. 99, 163-176