Human Genomics Lab
 
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Publications


Publications 1999 – present:

1999

  1. Stanforth PR, Ruthven MD, Gagnon J, Bouchard C, Leon AS, Rao DC, Skinner JS, Wilmore JH. Accuracy of prediction equations to estimate submaximal VO2max during cycle ergometry: The HERITAGE Family Study. Med Sci Sports Exerc  31:183-8, 1999.
  2. Perusse L, Chagnon YC, Weisnagel J, Bouchard C. The human obesity gene map: the 1998 update. Obes Res  7:111-29, 1999.
  3. Katzmarzyk PT, Perusse L, Bouchard C. Genetics of abdominal visceral fat levels. Am J Hum Biol  11:225-35, 1999.
  4. Rice T, Perusse L, Bouchard C, Rao DC. Familial aggregation of body mass index and subcutaneous fat measures in the longitudinal Québec Family Study. Genet Epidemiol 16:316-34, 1999.
  5. Chagnon YC, Chung WK, Perusse L, Chagnon M, Leibel RL, Bouchard C. Linkages and associations between the leptin receptor (LEPR) gene and human body composition in the Québec Family Study. Int J Obes  23:278-86, 1999.
  6. Dionne I, Després J-P, Bouchard C, Tremblay A. Gender difference in the effect of body composition on energy metabolism. Int J Obes  23:312-9, 1999.
  7. Rankinen T, Perusse L, Dériaz O, Thériault G, Chagnon M, Nadeau A, Bouchard C. Linkage of the Na,K-ATPase a2 and b1 genes with resting and exercise heart rate and blood pressure: cross-sectional and longitudinal observations from the Quebec Family Study. J Hypertens  17:339-49, 1999.
  8. An P, Rice T, Gagnon J, Borecki IB, Perusse L, Leon AS, Skinner JS, Wilmore JH, Bouchard C, Rao DC. Familial aggregation of resting blood pressure and heart rate in a sedentary population: The HERITAGE Family Study. Am J Hypertens 12:264-70, 1999.
  9. St-Amand J, Prud'homme D, Moorjani S, Nadeau A, Tremblay A, Bouchard C, Lupien PJ, Després J-P. Apolipoprotein E polymorphism and the relationships of physical fitness to plasma lipoprotein-lipid levels in men and women. Med Sci Sports Exerc  31:692-697, 1999.
  10. Rivera MA, Perusse L, Simoneau JA, Gagnon J, Dionne FT, Leon AS, Skinner JS, Wilmore JH, Province M, Rao DC, Bouchard C. Linkage between a muscle-specific CK gene marker and VO2max in the HERITAGE Family Study. Med Sci Sports Exerc  31:698-701, 1999.
  11. Bouchard C. La génétique du surpoids et de l'obésité. XXXIIe Congrès de l'Association des pédiatres de langue française. Arch Pediatr  6 (Suppl. 2):158-60, 1999.
  12. Perusse L, Bouchard C. Role of genetic factors in childhood obesity and in susceptibility to dietary variations. Proceedings of the XI Medical symposium of the Yrjö Jahnsson Foundation. Ann Med  31 (Suppl. 1):19-25, 1999.
  13. Després J-P, Gagnon J, Bergeron J, Couillard C, Leon AS, Rao DC, Skinner JS, Wilmore JH, Bouchard C. Plasma post-heparin lipase activities in the HERITAGE Family Study: The reproducibility, gender differences, and associations with lipoprotein levels. Clin Biochem 32:157-65, 1999.
  14. Rice T, Sjöström CD, Perusse L, Rao DC, Sjöström L, Bouchard C. Segregation analysis of body mass index in large sample selected for obesity: The Swedish Obese Subjects Study. Obes Res  7:246-55, 1999.
  15. Katzmarzyk P, Malina RM, Song TMK, Bouchard C. Physique, subcutaneous fat, adipose tissue distribution, and risk factors in the Québec Family Study. Int J Obes  23:476-84, 1999.
  16. Katzmarzyk P, Perusse L, Malina RM, Bouchard C. Seven-year stability of indicators of obesity and adipose tissue distribution in the Canadian population. Am J Clin Nutr  69:1123-9, 1999.
  17. Hong Y, Rice T, Després J-P, Gagnon J, Nadeau A, Bergeron J, Perusse L, Bouchard C, Leon AS, Skinner JS, Wilmore JH, Rao DC. Evidence of a major locus for lipoprotein lipase (LPL) activity in addition to a pleiotropic locus for both LPL and fasting insulin: results from the HERITAGE Family Study. Atherosclerosis  144:393-401, 1999.
  18. Katzmarzyk PT, Perusse L, Rao DC, Bouchard C. Familial risk of obesity and central adipose tissue distribution in the general Canadian population. Am J Epidemiol  149:933-42, 1999.
  19. Katzmarzyk PT, Rankinen T, Perusse L, Dériaz O, Tremblay A, Borecki I, Rao DC, Bouchard C. Linkage and association of the sodium potassium-adenosine triphosphatase a2 and b1 genes with respiratory quotient and resting metabolic rate in the Québec Family Study. J Clin Endocrinol Metab  84:2093-7, 1999.
  20. Clasey JL, Bouchard C, Teates CD, Riblett JE, Thorner MO, Hartman ML, Weltman A. The use of anthropometric and dual-energy X-ray absorptiometry (DXA) measures to estimate total abdominal and abdominal visceral fat in men and women. Obes Res 7:256-64, 1999.
  21. Perusse L, Bouchard C. Genotype-environment interaction in human obesity. Nutr Rev  57:S31-S38, 1999.
  22. Rivera MA, Perusse L, Gagnon J, Dionne FT, Leon AS, Rao DC, Skinner JS, Wilmore JH, Sjöström L, Bouchard C. A mitochondrial DNA D-loop polymorphism and obesity in three cohorts of women. Int J Obes  23: 666-8, 1999.
  23. Eisenmann JC, Katzmarzyk PT, Thériault G, Song TMK, Malina RM, Bouchard C. Physical activity and pulmonary function in youth: The Québec Family Study. Pediatr Exerc Sci  11:208-17, 1999.
  24. Wilmore JH, Despres J-P, Stanforth PR, Mandel S, Rice T, Gagnon G, Leon AS, Rao DC, Skinner JS, Bouchard C.  Alterations in body weight and composition consequent to 20 wk of endurance training: the HERITAGE Family Study.  Am J Clin Nutr  70:346-52, 1999.
  25. Bouchard C, An P, Rice T, Skinner JS, Wilmore JH, Gagnon J, Perusse L, Leon AS, Rao DC. Familial aggregation of VO2max response to exercise training: results from the HERITAGE Family Study.  J Appl Physiol 87:1003-8, 1999.
  26. Rankinen T, Gagnon J, Perusse L, Rice T, Leon AS, Skinner JS, Wilmore JH, Rao DC, Bouchard C.  Body fat, resting and exercise blood pressure and the angiotensinogen M235T polymorphism: The HERITAGE family study.  Obes Res  7:423-30, 1999.
  27. Sun G, Gagnon J, Chagnon YC, Perusse L, Despres J-P, Leon AS, Wilmore JH, Skinner JS, Borecki I, Rao DC, Bouchard C.  Association and linkage between an insulin-like growth factor-1 gene polymorphism and fat free mass in the HERITAGE family study. Int J Obes  23:929-35, 1999.
  28. Pritchard J, Despres J-P, Gagnon J, Tchernof A, Nadeau A, Tremblay A, and Bouchard C.  Plasma adrenal, gonadal, and conjugated steroids following long-term exercise-induced negative energy balance in identical twins.  Metabolism  48:1120-7, 1999.
  29. Vaisanen SB, Humphries SE, Luong L-A, Penttila I, Bouchard C, and Rauramaa R. Regular exercise, plasminogen activator inhibitor-1 (PAI-1) activity and the 4G/5G promoter polymorphism in the PAI-1 gene. Thromb Haemost  82:1117-20, 1999.
  30. Vohl M-C, Lamarche B, Pascot A, Leroux G, Prud'homme D, Bouchard C, Nadeau A, Despres J-P.  Contribution of the cholesteryl ester transfer protein gene TaqlB polymorphism to the reduced plasma HDL-cholesterol levels found in abdominal obese men with the features of the insulin resistance syndrome.  Int J Obes  23:918-25, 1999.
  31. Pascot A, Lemieux S, Lemieux I, Prud'homme D, Tremblay A, Bouchard C, Nadeau A, Couillard C, Tchernof A, Bergeron J, and Despres J-P.  Age-related increase in visceral adipose tissue and body fat and the metabolic risk profile of premenopausal women. Diabetes Care  22:1471-8, 1999.
  32. Rice T, Hong Y, Perusse L, Despres J-P, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Bouchard C, Rao DC.  Total body fat and abdominal visceral fat response to exercise training in the HERITAGE Family Study:  Evidence for major locus but no multifactorial effects.  Metabolism  48:1278-86, 1999.
  33. Lemieux I, Pascot A, Tchernof A, Bergeron J, Prud'homme D, Bouchard C, Despres J-P. Visceral adipose tissue and low-density lipoprotein particle size in middle-aged versus young men. Metabolism  48:1322-7, 1999.
  34. Skinner JS, Wilmore KM, Jaskolska A, Jaskolski A, Daw EW, Rice T, Gagnon J, Leon AS, Wilmore JH, Rao DC, Bouchard C.  Reproducibility of maximal exercise test data in the HERITAGE Family Study.  Med Sci Sports Exerc  31:1623-8, 1999.
  35. Katzmarzyk PT, Perusse L, Rao DC, Bouchard C.  Spousal resemblance and risk of 7-year increases in obesity and central adiposity in the Canadian population. Obes Res 7:545-51, 1999.
  36. Rankinen T, Kim S-Y, Perusse L, Despres J-P, Bouchard C.  The prediction of abdominal visceral fat level from body composition and anthropometry: ROC analysis.  Int J Obes  23:801-9, 1999.
  37. Couillard C, Bergeron N, Prud’homme D, Bergeron J, Tremblay A, Bouchard C, Mauriege P, Despres J-P.  Gender Difference in Postprandial Lipemia Importance of Visceral Adipose Tissue Accumulation.  Arterioscler Thromb Vasc Biol  19:2448-55, 1999.
  38. Katzmarzyk PT, Malina RM, Bouchard C.  Physical activity, physical fitness, and coronary heart disease risk factors in youth: The Quebec Family Study.  Prev Med  29:555-62, 1999.
  39. Bouchard C.  Physical Inactivity.  Can J Cardiol 15: 89G-92G, 1999.
  40. Helminen A, Rankinen T, Halonen P, Väisänen S, Rauramaa R. Positive and negative life changes and LDL cholesterol. J Biosoc Sci 1999;31:269-277.
  41. Reeder B, Bouchard C.  Obesity and cardiovascular diseases.  Can J Cardiol 15: 69G-72G, 1999

 

2000

  1. Skinner JS, Wilmore KM, Krasnoff JB, Jaskolski A, Jaskolska A, Gagnon J, Province MA, Leon AS, Rao DC, Wilmore JH, Bouchard C.  Adaptation to a standardized training program and changes in fitness in a large heterogeneous population: the HERITAGE Family Study. Med Sci Sports Exerc  32:157-61, 2000.
  2. Rankinen T, Perusse L, Borecki I, Chagnon YC, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Rao DC, Bouchard C.  The Na+-K+-ATPase a2 gene and trainability of cardiorespiratory endurance: the HERITAGE Family Study. J Appl Physiol  88:346-51, 2000.
  3. Bouchard C, Rankinen T, Chagnon YC, Rice T, Perusse L, Gagnon J, Borecki I, An P, Leon AS, Skinner JS, Wilmore JH, Province M, Rao DC.  Genomic scan for maximal oxygen uptake and its response to training in the HERITAGE Family Study. J Appl Physiol  88:551-9, 2000.
  4. An P, Rice T, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Bouchard C, Rao DC.  Cross-Trait Familial Resemblance for Resting Blood Pressure and Body Composition and Fat Distribution: The HERITAGE Family Study. Amer J Hum Biol 12:32-41, 2000.
  5. Dionne I, Almeras N, Bouchard C, Tremblay A.  The association between vigorous physical activities and fat deposition in male adolescents. Med Sci Sports Exerc 32:392-5, 2000.
  6. Chagnon YC, Borecki IB, Perusse L, Roy S, Lacaille M, Chagnon M, Ho-Kim MA, Rice T, Province MA, Rao DC, Bouchard C.  Genome-Wide Search for Genes Related to the Fat-Free Body Mass in the Quebec Family Study.  Metabolism 49:203-7, 2000.
  7. Chagnon YC, Perusse L, Weisnagel SJ, Rankinen T, Bouchard C.  The Human Obesity Gene Map: The 1999 Update. Obes Res 8:89-117, 2000.
  8. Rankinen T, Perusse L, Gagnon J, Chagnon YC, Leon AS, Skinner JS, Wilmore JH, Rao DC, Bouchard C.  Angiotensin-converting enzyme ID polymorphism and fitness phenotype in the HERITAGE Family Study. J Appl Physiol 88:1029-35, 2000.
  9. An P, Rice T, Gagnon J, Borecki IB, Bergeron J, Despres J-P, Leon AS, Skinner JS, Wilmore JH, Bouchard C, Rao DC.  Segregation Analysis of Apolipoproteins A-1 and B-100 Measured Before and After an Exercise Training Program: The HERITAGE Family Study. Arterioscler Thromb Vasc Biol 20:807-14, 2000.
  10. Chagnon YC, Wilmore JH, Borecki IB, Gagnon J, Perusse L, Chagnon M, Collier GR, Leon AS, Skinner JS, Rao DC, Bouchard C. Associations between the Leptin Receptor Gene and Adiposity in Middle-Aged Caucasian Males from the HERITAGE Family Study. J Clin Endocrinol Metab 85:29-34, 2000.
  11. An P, Rice T, Gagnon J, Hong Y, Leon AS, Skinner JS, Wilmore JH, Bouchard C, Rao DC.  A genetic study of dehydroepiandrosterone sulfate measured before and after a 20-week endurance exercise training program: The HERITAGE Family Study.  Metabolism 49:298-304, 2000.
  12. Katzmarzyk P, Perusse L, Rao DC, Bouchard C.  Familial risk ratios for high and low physical fitness levels in the Canadian population. Med Sci Sports Exer 32:614-9, 2000.
  13. Sun G, Chagnon M, Bouchard C.  A common polymorphism in the human insulin-like growth factor binding protein 3 gene. Mol Cell Probes 14:55-56, 2000.
  14. Couillard C, Gagnon J, Bergeron J, Leon AS, Rao DC, Skinner JS, Wilmore JH, Despres J-P Bouchard C. Contribution of Body Fatness and Adipose Tissue Distribution to the Age Variation in Plasma Steroid Hormone Concentrations in Men: The HERITAGE Family Study. J Clin Endocrinol Metab 85:1026-31, 2000
  15. Hong Y, Despres J-P, Rice T, Nadeau A, Province MA, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Bouchard C, Rao DC.  Evidence of Pleiotropic Loci for Fasting Insulin, Total Fat Mass, and Abdominal Visceral Fat in a Sedentary Population: The HERITAGE Family Study. Obes Res  8:151-9, 2000.
  16. Perusse L, Rice T, Province MA, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Rao DC, Bouchard C. Familial Aggregation of Amount and Distribution of Subcutaneous Fat and Their Responses to Exercise Training in the HERITAGE Family Study. Obes Res 8:140-50, 2000.
  17. Ukkola, O, Tremblay A, Despres J-P, Chagnon YC, Campfield LA, and Bouchard C. Leptin Receptor GLN223Arg Variant is Associated with a Cluster of Metabolic Abnormalities in Response to Long-Term Overfeeding. J Intern Med 248: 435-39, 2000.
  18. Garenc C, Perusse L, Gagnon J, Chagnon YC, Bergeron J, Despres J-P, Province MA, Leon AS, Skinner JS, Wilmore JH, Rao DC, Bouchard C. Linkage and Association Studies of the Lipoprotein Lipase Gene with Postheparin Plasma Lipase Activities, Body Fat and Plasma Lipid and Lipoprotein Concentrations: The HERITAGE Family Study. Metabolism 49:432-9, 2000.
  19. Katzmarzyk PT, Malina RM, Perusse L, Rice T, Province MA, Rao DC, Bouchard C. Familial Resemblance in Fatness and Fatness Distribution. Am J Hum Biol 12:395-404, 2000
  20. Leon AS, Rice T, Mandel S, Despres J-P, Bergeron J, Gagnon J, Rao DC, Skinner JS, Wilmore JH, Bouchard C. Blood Lipid Response to 20 weeks of Supervised Exercise in a Large Biracial Population: The HERITAGE Family Study. Metabolism 49:513-20, 2000.
  21. Rosmond R, Chagnon YC, Holm G, Chagnon M, Perusse L, Lindell K, Carlsson B, Bouchard C, and Bjorntorp P. A Glucocorticoid Receptor Gene Marker is Associated with Abdominal Obesity, Leptin, and Dysregulation of the Hypothalamic-Pituitary-Adrenal Axis. Obes Res 8:211-8, 2000
  22. An P, Rice T, Perusse L, Borecki IB, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Bouchard C, and Rao DC. Complex Segregation Analysis of Blood Pressure and Heart Rate Measured Before and After a 20-Week Endurance Exercise Training Program: the HERITAGE Family Study.  Am J Hypertension 13:488-97, 2000 
  23. Rosmond R, Chagnon YC, Holm G, Chagnon M, Perusse L, Lindell, K, Carlsson B, Bouchard C. Bjorntorp P. Hypertension in obesity and the leptin receptor gene locus. J Clin Endocrinol Metab  85:3126-31, 2000.
  24. Rice T, Rankinen T, Province MA, Chagnon YC, Perusse L, Borecki IB, Bouchard C, Rao DC.  Genome-Wide Linkage Analysis of Systolic and Diastolic Blood Pressure, The Quebec Family Study. Circulation 102:1956-63 2000.
  25. Rankinen T, Wolfarth B, Simoneau J-A, Maier-Lenz D, Rauramaa R, Rivera MA, Boulay MR, Chagnon YC, Perusse L, Keul J, Bouchard C.  No association between the angiotensin-converting enzyme ID polymorphism and elite endurance athlete status. J Appl Physiol 88:1571-5, 2000.
  26. Rosmond R, Ukkola O, Chagnon M, Bouchard C, Bjorntorp P. Polymorphisms of the beta2-adrenergic receptor gene (ADRB2) in relation to cardiovascular risk factors in men. J Intern Med 248:239-44, 2000
  27. Rankinen T, Gagnon J, Perusse L, Chagnon YC, Rice T, Leon AS, Skinner JS, Wilmore JH, Rao DC, Bouchard C.  AGT M235T and ACE ID polymorphisms and exercise blood pressure in the HERITAGE Family Study. Am J Physiol Heart Circ Physiol 279: H368-74, 2000
  28. Couillard C, Mauriege P, Imbeault P, Prud’homme D, Nadeau A, Tremblay A, Bouchard C, Despres J-P. Hyperleptinemia is more closely associated with adipose cell hypertrophy than with adipose tissue hyperplasia.  Int J Obes 24:782-8, 2000
  29. Katzmarzyk PT, Perusse L, Rao DC, Bouchard C. Familial Risk of Overweight and Obesity in the Canadian Population Using the WHO/NIH Criteria. Obes Res 8:194-7, 2000
  30. Katzmarzyk P, Perusse L, Rice T, Gagnon J, Skinner JS, Wilmore JH, Leon AS, Rao DC, Bouchard C. Familial resemblance for coronary heart disease risk: The HERITAGE Family Study. Ethn Dis 10: 138-47, 2000
  31. Wolfarth B, Rivera MA, Oppert JM, Boulay MR, Dionne FT, Chagnon M, Gagnon J, Chagnon YC, Perusse L, Keul J, Bouchard C. A polymorphism in the alpha 2a adrenoceptor gene and endurance athlete status. Med Sci Sports Exerc 32:1709-12, 2000
  32. Rosmond R, Chagnon YC, Chagnon M, Perusse L, Bouchard C, Bjorntorp P. A Polymorphism of the 5’-flanking region of the glucocorticoid receptor gene locus is associated with basal cortisol secretion in men. Metabolism 49:1197-9, 2000.
  33. Rauramaa R, Vaisanen SB, Kuhanen R, Penttila I, Bouchard C. The Rsai Polymorphism in the ?-fibrinogen Gene and Response of Plasma Fibrinogen to Physical Training. Thromb Haemost 83:803-6, 2000.
  34. Despres JP, Couillard C, Gagnon J, Bergeron J, Leon AS, Rao DC, Skinner JS, Wilmore JH, Bouchard C. Race, Visceral Adipose Tissue, Plasma Lipids, and Lipoprotein Lipase Activity in Men and Women. The Health, Risk Factors, Exercise Training, and Genetics (HERITAGE) Family Study. Arterioscler Thromb Vasc Biol  20:1932-8, 2000.
  35. Katzmarzyk PT, Rankinen T, Perusse L, Malina RM, Bouchard C.  7- Year Stability of Blood Pressure in the Canadian Population.  Prev Med 31: 403-9, 2000.
  36. Hong Y, Rice T, Gagnon J, Perusse L, Province M, Bouchard C, Leon AS, Skinner JS, Wilmore JH, Rao DC, Despres JP. Familiality of triglyceride and LPL response to exercise training:  the HERITAGE Study. Med Sci Sports Exerc  32:1438-44, 2000
  37. Stanforth PR, Gagnon J, Rice T, Bouchard C, Leon AS, Rao DC, Skinner JS, Wilmore JH. Reproducibility of Resting Blood Pressure and Heart Rate Measurements:  The HERITAGE Family Study. Ann Epidemiol 10: 271-77, 2000
  38. An P, Rice T, Borecki IB, Perusse L, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Bouchard C, Rao DC.  Major Gene Effect on Subcutaneous Fat Distribution in a Sedentary Population and Its Response to Exercise Training: The HERITAGE Family Study.  Am J Hum Biol 12:600-9, 2000.
  39. An P, Rice T, Gagnon J, Hong Y, Leon AS, Skinner JS, Wilmore JH, Bouchard C, Rao DC. A Genetic Study of Sex Hormone-Binding Globulin Measured Before and After a 20-Week Endurance Exercise Training Program: The HERITAGE Family Study.  Metabolism 49:1014-20, 2000
  40. Ukkola O, Rankinen T, Weisnagel SJ, Sun G, Perusse L, Chagnon YC, Despres JP, Bouchard C.  Interactions Among the a2-, b2- and b3-Adrenergic Receptor Genes and Obesity-Related Phenotypes in the Quebec Family Study. Metabolism  49:1063-70, 2000.
  41. Katzmarzyk PT, Perusse L, Tremblay A, Bouchard C. No association between resting metabolic rate or respiratory exchange ratio and subsequent changes in body mass and fatness: 5 ½ year follow up of the Quebec Family Study. Eur J Clin Nutr. 54:610-4, 2000.
  42. Rankinen T, Hietanen E, Vaisanen S, Lehtio M, Penttila I, Bouchard C, Rauramaa R. Relationship between Lipid Peroxidation and Plasma Fibrinogen in Middle-Aged Men. Thromb Res  99:453-9, 2000.
  43. York D and Bouchard C. How Obesity Develops: Insights from the New Biology. Endocrine  13: 143-54, 2000.
  44. Rice T, Rao R, Perusse L, Bouchard C and Rao DC. Tracking of Familial Resemblance for Resting Blood Pressure over Time in the Quebec Family Study.  Hum Biol 72:415-31, 2000.
  45. Doucet E, St-Pierre S, Almeras N, Mauriege P, Despres JP, Richard D, Bouchard C and Tremblay A. Fasting insulin levels influence plasma leptin levels independently from the contribution of adiposity: evidence from both a cross-sectional and an intervention study. J Clin Endocrinol Metab 85: 4231-7, 2000.
  46. Perusse L and Bouchard C. Gene-diet interactions in obesity. Am J Clin Nutr 72: 1285S-90S, 2000.
  47. Rankinen T, Rice T, Perusse L, Chagnon YC, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Rao DC, and Bouchard C. NOS3 Glu298Asp Genotype and Blood Pressure Response to Endurance Training the Heritage Family Study. Hypertension  36:885-9, 2000.
  48. Bouchard C. Clinical Implications of Basic Research: Inhibition of Food Intake by Inhibitors of Fatty Acid Synthase.  N Eng J Med 343: 1888-9, 2000.
  49. Eisenmann JC, Katzmarzyk PT, Theriault G, Song TMK, Malina RM, Bouchard C.  Cardiac dimensions, physical activity, and submaximal working capacity in youth of the Quebec Family Study. Eur J Appl Physiol  81:40-6, 2000.
  50. Lemieux I, Couillard C, Pascot A, Bergeron N, Prud’homme D, Bergeron J, Tremblay A, Bouchard C, Mauriege P, Despres JP.  The Small, Dense LDL Phenotype as a Correlate of Postprandial Lipemia in Men.  Atherosclerosis, 153: 423-32, 2000.
  51. An P, Rice T, Gagnon J, Leon AS, Skinner JS, Bouchard C, Rao DC, Wilmore JH. Familial aggregation of stroke volume and cardiac output during submaximal exercise: The HERITAGE Family Study. Int J Sports Med 21: 566-72, 2000.
  52. Ravussin E and Bouchard C. Human genomics and obesity: finding appropriate drug targets. Eur J Pharmacol 410: 131-45, 2000.
  53. Rauramaa R, Vaisanen SB, Luong L-A, Schmidt-Trucksass A, Penttila IM, Bouchard C, Toyry J, and Humphries SE.  Stromelysin-1 and interleukin-6 gene promoter polymorphisms are determinants of asymptomatic carotid artery atherosclerosis.  Arterioscler Thromb Vasc Biol 20: 2657-62, Dec 2000.
  54. Couillard C, Bergeron N, Bergeron J, Pascot A, Maurieger P, Tremblay, A, Prud’homme D, Bouchard C, and Despres JP.  Metabolic heterogeneity underlying postprandial lipemia among men with low fasting high density lipoprotein cholesterol concentrations.  J Clin Endocrinol Metab 85: 4575-4582, 2000.
  55. Katzmarzyk PT, Malina RM, Perusse L, Rice T, Province MA, Rao DC, and Bouchard C. Familial resemblance for physique: heritabilities for somatotype components. Ann Hum Biol Vol 27, No 5:467-477, 2000.
  56. Huuskonen J, Vaisanen SB, Kroger H, Jurvelin C, Bouchard C, Alhava E, and Rauramaa R.  Determinants of bone mineral density in middle aged men: A population-based study. Osteoporos Int 11:702-708, 2000.
  57. Fogelholm M, Rankinen T, Isokääntä M, Kujala U, Uusitupa M. Growth, dietary intake and trace element status in pubescent athletes and schoolchildren: a 2-year follow-up. Med Sci Sports Exerc 2000;32:738-746.

2001:

  1. Wilmore JH, Stanforth PR, Gagnon J, Rice T, Mandel S, Leon AS, Rao DC, Skinner JS, Bouchard C. Cardiac output and stroke volume changes with endurance training: The HERITAGE Family Study. Medicine and Science in Sports and Exercise 33:99-106, 2001
  2. Campbell PT, Katzmarzyk PT, Malina RM, Rao DC, Perusse L, Bouchard C. Prediction of physical activity and PWC150 in young adulthood from childhood and adolescence with consideration of parental measures. Am J Hum Biol 13:190-6, 2001.
  3. Larose M, Bouchard C, and Chagnon YC.  A new gene related to human obesity identified by suppression subtractive hybridization. Int J Obes 25:770-6, 2001.
  4. Weisnagel SJ, Rankinen T, Nadeau A, Rao DC, Chagnon YC, Perusse L, Bouchard C. Decreased fasting and oral glucose stimulated C-peptide in nondiabetic subjects with sequence variants in the sulfonylurea receptor 1 gene. Diabetes 2001;50:697-702
  5. Perusse L, Chagnon Y, Weisnagel SJ, Rankinen T, Snyder E, Sands J, Bouchard C. The human obesity gene map: the 2000 update. Obes Res 2001;9:135-169
  6. Ukkola O, Perusse L, Weisnagel SJ, Bergeron J, Despres J-P, Rao DC, and Bouchard C. Interactions Among the Glucocorticoid Receptor, Lipoprotein Lipase and Adrenergic Receptor Genes and Plasma Insulin and Lipid Levels in the Quebec Family Study. Metabolism 50:246-52, 2001
  7. Yoshioka M, Doucet E, St-Pierre S, Almeras N, Richard D, Labrie A, Despres JP, Bouchard C, and Tremblay A.  Impact of high-intensity exercise on energy expenditure, lipid oxidation and body fatness. Int J Obes 25:332-339, 2001.
  8. Katzmarzyk P, Perusse L, Malina RM, Bergeron J, Despres JP, and Bouchard C. Stability of indicators of the metabolic syndrome from childhood and adolescence to young adulthood: the Quebec Family Study. J Clin Epidemiol 54:190-195, 2001.
  9. Perusse L, Rice T, Chagnon YC, Despres JP, Lemieux S, Roy S, Lacaille M, Ho-Kim MY, Chagnon M, Province MA, Rao DC, and Bouchard C.  A genome-wide scan for abdominal fat assessed by computed tomography in the Quebec Family Study. Diabetes 50:614-621, 2001.
  10. Wauters M, Mertens I, Chagnon M, Rankinen T, Considine RV, Chagnon YC, Van Gaal LF, Bouchard C. Polymorphisms in the leptin receptor gene, body composition and fat distribution in overweight and obese women. Int J Obes Relat Metab Disord 2001;25:714-720
  11. Rankinen T, Perusse L, Rauramaa R, Rivera MA, Wolfarth B, Bouchard C. The human gene map for performance and health-related fitness phenotypes. Med Sci Sports Exerc 2001;33:855-867.
  12. Bouchard C, Rankinen T. Individual differences in response to regular physical activity. Med Sci Sports Exerc. 2001;33:S446-S451.
  13. Wilmore JH, Stanforth PR, Gagnon J, Rice T, Mandel S, Leon AS, Rao DC, Skinner JS and Bouchard C. Heart rate and blood pressure changes with endurance training: The HERITAGE Family Study. Medicine and Science in Sports and Exercise 33:107-116, 2001.
  14. Ukkola O, Rosmond R, Tremblay A and Bouchard C.  Glucocorticoid receptor Bcl I variant is associated with an increased atherogenic profile in response to long-term overfeeding.  Atherosclerosis 157:221-224, 2001.
  15. Doucet E, St-Pierre S, Almeras N, Despres J-P, Bouchard C, and Tremblay A.  Evidence for the existence of adaptive thermogenesis during weight loss.  British J Nutr 85:715-723, 2001.
  16. Rivera M, Echegaray M, Rankinen T, Pérusse L, Rice T, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Rao DC and Bouchard C. Angiogenin gene-race interaction for resting and exercise BP phenotypes: The HERITAGE Family Study. Journal of Applied Physiology 90: 1232-1238, 2001.
  17. Skinner JS, Jaskólski A, Jaskólska A, Krasnoff J, Gagnon J, Leon AS, Rao DC, Wilmore JH and Bouchard C. Age, sex, race, initial fitness and response to training: The HERITAGE Family Study. Journal of Applied Physiology 90:1770-1776, 2001.
  18. Chagnon YC, Rice T, Pérusse L, Borecki IB, Ho-Kim MA, Lacaille M, Pare C, Bouchard L, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Rao DC and Bouchard C. Genome scan for genes affecting body composition before and after training in Caucasians from HERITAGE. Journal of Applied Physiology 90:1777-1787, 2001.
  19. Katzmarzyk PT, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Rao DC and Bouchard C. Fitness, fatness and estimated coronary heart disease risk: The HERITAGE Family Study.  Medicine and Science in Sports and Exercise 33:585-590, 2001.
  20. Ukkola O, Ravussin E, Jacobson P, Snyder EE, Chagnon M, Sjostrom L and Bouchard C.  Mutations in the preproghrelin/ghrelin gene associated with obesity in humans. J Clin Endocrinol Metab 86(8): 3996-3999, 2001.
  21. Pérusse L, Gagnon J, Province MA, Rao DC, Wilmore JH, Leon AS, Bouchard C and Skinner JS. Familial aggregation of submaximal aerobic performance in the HERITAGE Family Study. Medicine and Science in Sports and Exercise 33:597-604, 2001
  22. Ukkola O. and Bouchard C.  Clustering of metabolic abnormalities in obese individuals: the role of genetic factors. Ann Med 33: 79-90, 2001.
  23. Rosmond R, Chagnon M, Bouchard C and Bjorntorp P.  G-308A polymorphism of the tumor necrosis factor a gene promoter and salivary cortisol secretion. J Clin Endocrinol Metab Vol 86, No.5:2178-2180, 2001
  24. Rosmond R, Bouchard C and Bjorntorp P.  Tsp509I polymorphism in exon 2 of the glucocorticoid receptor gene in relation to obesity and cortisol secretion: cohort study.  BMJ 322: 652-653, 2001
  25. Garenc C, Pérusse L, Rankinen T, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Rao DC and Bouchard C. The Trp64Arg polymorphism in the b3-adrenergic receptor gene is not associated with training-induced changes in body composition: The HERITAGE Family Study. Obesity Research 9: 337-341, 2001.
  26. Ukkola O, Gagnon J, Rankinen T, Thompson PA, Hong Y, Pérusse L, Leon AS, Rao DC, Skinner JS, Wilmore JH and Bouchard C. Age, body mass index, race and other determinants of steroid hormone variability: The HERITAGE Family Study. European Journal of Endocrinology 145: 1-9, 2001.
  27. Katzmarzyk P, Leon AS, Rankinen T, Gagnon J, Skinner JS, Wilmore JH, Rao DC, Bouchard C. Changes in blood lipids consequent to endurance training related to changes in body fatness and aerobic fitness. Metabolism 50: 841-848, 2001.
  28. Campbell PT, Katzmarzyk PT, Malina RM, Rao DC, Perusse L and Bouchard C.  Stability of adiposity phenotypes from childhood and adolescence into young adulthood with contribution of parental measures.  Obes Res 9(7):394-400, 2001
  29. Couillard C, Després JP, Lamarche B, Bergeron J, Gagnon J, Leon AS, Rao DC, Skinner JS, Wilmore JH and Bouchard C. Effect of endurance exercise training on plasma HDL cholesterol levels depend on the levels of triglycerides. Evidence from men of the Health, Risk Factors, Exercise Training and Genetics (HERITAGE) Family Study. Arteriosclerosis, Thrombosis and Vascular Biology 21: 1226 – 1232, 2001.
  30. Wauters M, Mertens I, Rankinen T, Chagnon M, Bouchard C, Van Gaal L. Leptin receptor gene polymorphisms are associated with insulin in obese women with impaired glucose tolerance. J Clin Endocrinol Metabol 2001;86:3227-32
  31. Rankinen T, An P, Sun G, Rice T, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Rao DC and Bouchard C. Genomic scan for exercise blood pressure in the HERITAGE Family Study. Hypertension 38: 30-37, 2001.
  32. Ukkola O and Bouchard C.  Genetic factors and childhood obesity.  Annales Nestle 59:59-68, 2001.
  33. Katzmarzyk PT. Rankinen T, Pérusse L, Rao DC, Bouchard C. Familial risk of high blood pressure in the Canadian population. Am J Hum Biol 2001;13:620-5
  34. Rosmond R, Rankinen T, Chagnon M, Perusse L, Chagnon YC, Bouchard C, Bjorntorp P. Polymorphism in exon 6 of the dopamine D(2) receptor gene (DRD2) is associated with elevated blood pressure and personality disorders in men. J Hum Hypertens. 2001;15:553-8
  35. An P, Rice T, Gagnon J, Hong Y, Leon AS, Skinner JS, Wilmore JH, Bouchard C and Rao DC. Race differences in the pattern of familial aggregation for dehydroepiandrosterone sulfate and its responsiveness to training in the HERITAGE Family Study. Metabolism 50; 916-920, 2001.
  36. Hong Y, Gagnon J, Rice T, Pérusse L, Leon AS, Skinner JS, Wilmore JH, Bouchard C and Rao DC. Familial resemblance for free androgens and androgen glucuronides in sedentary Black and White individuals: The HERITAGE Family Study. Journal of Endocrinology 170; 485-492, 2001
  37. Garenc C, Pérusse L, Bergeron J, Chagnon YC, Gagnon J, Borecki IB, Leon AS, Skinner JS, Wilmore JH, Rao DC and Bouchard C. Evidence of LPL gene-exercise interaction for body fat and LPL activity: the HERITAGE Family Study. Journal of Applied Physiology 91:1334-40, 2001.
  38. Katzmarzyk PT, Craig CL and Bouchad C. Underweight, overweight and obesity: relationships with mortality in the 13-year follow-up of the Canada Fitness Survey.  J Clin Epidemiol 54:916-920, 2001.
  39. Seidell JC, Perusse L, Despres J-P, and Bouchard C.  Waist and hip circumferences have independent and opposite effects on cardiovascular disease risk factors: the Quebec Family Study.  Am J Clin Nutr 74:315-21, 2001.
  40. Hong Y, Weisnagel SJ, Rice T, Sun G, Mandel SA, Gu C, Rankinen T, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Bergman RN, Bouchard C and Rao DC. Familial resemblance for glucose and insulin metabolism indices derived from an intravenous glucose tolerance test in Blacks and Whites of the HERITAGE Family Study. Clinical Genetics 60:22-30, 2001.
  41. Rivera MA, Echegaray M, Rankinen T, Pérusse L, Rice T, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Rao DC and Bouchard C. TGF-B1 gene-race interactions for resting and exercise blood pressure in the HERITAGE Family Study. Journal of Applied Physiology 91:1808-1813, 2001.
  42. Gaskill S, Rice T, Bouchard C, Gagnon J, Rao DC, Skinner J, Wilmore J and Leon AS. Familial resemblance in ventilatory threshold: the HERITAGE Family Study. Medicine and Science in Sports and Exercise 33:1832-1840, 2001.
  43. An P, Rice T, Gagnon J, Borecki IB, Rankinen T, Gu C, Leon AS, Skinner JS, Wilmore JH, Bouchard C and Rao DC. Population differences in the pattern of familial aggregation for sex hormone binding globulin and its response to exercise training: The HERITAGE Family Study. Am J Hum Biol 13:832-837, 2001.
  44. An P, Rosmond R, Borecki IB, Ukkola O, Rice T, Gagnon J, Rankinen T, Leon AS, Skinner JS, Wilmore JH, Bouchard C and Rao DC. Genome-wide linkage scan to detect loci influencing levels of dehydroepiandrosterones in the HERITAGE Family Study. Metabolism 50: 1315-1322, 2001.
  45. Wilmore JH, Green JS, Stanforth PR, Gagnon J, Rankinen T, Leon AS, Rao DC, Skinner JS, Bouchard C. Relationship of changes in maximal and submaximal aerobic fitness to changes in cardiovascular disease and non-insulin-dependent diabetes mellitus risk factors with endurance training: The HERITAGE Family Study.  Metabolism 50: 1255-63, 2001
  46. Gaskill SE, Walker AJ, Serfass RA, Bouchard C, Gagnon J, Rao DC, Skinner JS, Wilmore JH and Leon AS. Changes in ventilatory threshold with exercise training in a sedentary population: The HERITAGE Family Study. International Journal of Sports Medicine 22: 586-592, 2001.
  47. Ukkola O, Tremblay A, Sun G, Chagnon YC and Bouchard C.  Genetic variation at the uncoupling protein 1, 2 and 3 loci and the response to long-term overfeeding.  Eur J Clin Nutr 55:1008-1015, 2001.
  48. Fortier MD, Katzmarzyk PT, Malina RM and Bouchard C.  Seven-year stability of physical activity and musculoskeletal fitness in the Canadian population. Med Sci Sports Exerc, 33(11):1905-1911, 2001
  49. Ukkola O, Tremblay A and Bouchard C.  Beta-2 adrenergic receptor variants are associated with subcutaneous fat accumulation in response to long-term overfeeding. Int J Obes 25: 1604-8, 2001.
  50. Katzmarzyk PT, Perusse L, Rice T, Rao DC and Bouchard C.  Familial aggregation of seven-year changes in blood pressure in Canada.  Can J Cardiol 17(12):1267-1274, 2001
  51. Ravussin E, Tschop M, Morales S, Bouchard C and Heiman ML. Plasma ghrelin concentration and energy balance: overfeeding and negative energy balance studies in twins. J Clin Endocrinol Metab 686: 4547-4551, 2001.
  52. Katzmarzyk PT, Gledhill N, Perusse L, and Bouchard C. Familial aggregation of 7-year changes in musculoskeletal fitness. J Gerontol, 56A(12): B497-B502, 2001.
  53. Ukkola O, Garenc C, Perusse L, Bergeron J, Despres J-P, Rao DC and Bouchard C.  Genetic variation at the lipoprotein lipase locus and plasma lipoprotein and insulin levels in the Quebec Family Study. Arteriosclerosis 158: 199-206, 2001.
  54. Ukkola O, Sun G and Bouchard C.  Insulin-like growth factor 2 (IGF2) and IGF-binding protein 1 (IGFBP1) gene variants are associated with overfeeding-induced metabolic changes.  Diabetologia 44: 2231-2236, 2001.
  55. Lanouette C-M, Giacobino J-P, Perusse L, Lacaille M, Yvon C, Chagnon M, Kuhne F, Bouchard C, Muzzin P and Chagnon YC.  Association between uncoupling protein 3 gene and obesity-related phenotypes in the Quebec Family Study.  Mol Med 7(7): 433-441, 2001
  56. Rosmond R, Chagnon M, Bouchard C, and Bjorntorp P.  A polymorphism in the regulatory region of the corticotropin-releasing hormone gene in relation to cortisol secretion, obesity, and gene-gene interaction.  Metabolism 50(9): 1059-1062, 2001.
  57. Rosmond R, Chagnon M, Bouchard C and Bjorntorp P. A missense mutation in the human melanocortin-4 receptor gene in relation to abdominal obesity and salivary cortisol. Diabetologia 44: 1335-1338, 2001
  58. Heo M, Leibel RL, Boyer BB, Chung WK, Koulu M, Karvonen MK, Pesonen U, Rissanen A, Laakso M, Uusitupa MIJ, Chagnon Y, Bouchard C, Donohoue PA, Burns TL, Shuldiner AR, Silver K, Andersen RE, Pedersen O, Echwald S, Sorensen TIA, Behn P, Permutt MA, Jacobs KB, Elston RC, Hoffman DJ and Allison DB.  Pooling analysis of genetic data: the association of leptin receptor (LEPR) polymorphisms with variables related to human adiposity. Genetics 159:1163-1178, 2001.
  59. Ukkola O, Perusse L, Chagnon YC, Despres J-P and Bouchard C.  Interactions among the glucocorticoid receptor, lipoprotein lipase and adrenergic receptor genes and abdominal fat in the Quebec Family Study. Int J Obes 25: 1332-1339, 2001
  60. Bergeron J, Couillard C, Després JP, Gagnon J, Leon AS, Rao DC, Skinner JS, Wilmore JH, Bouchard C. Race differences in the response of postheparin plasma lipoprotein lipase and hepatic lipase activities to endurance exercise training in men. Results from the HERITAGE Family Study. Atherosclerosis 159:399-406, 2001.
  61. Bouchard C. The genetics of human obesity: recent progress. Bulletin et Memoires de l’Academie royale de Medecine de Belgique.  156(10-11-12): 455-464, 2001.
  62. Clasey JL, Weltman A, Patrie J, Weltman JY, Pezzoli S, Bouchard C, Thorner MO and Hartman ML. Abdominal visceral fat and fasting insulin are important predicators of 24-hour GH release independent of age, gender and other physiological factors.  J Clin Endocrinol Metab 86: 3845-3852, 2001.

2002

  1. Katzmarzyk PT, Hebebrand J and Bouchard C. Spousal resemblance in the Canadian population: implications for the obesity epidemic. Int J Obes 26: 241-246, 2002.
  2. Leon AS, Gaskill SE, Rice T, Bergeron J, Gagnon J, Rao DC, Skinner JS, Wilmore JH and Bouchard C. Variability in the response of HDL cholesterol to exercise training in the HERITAGE Family Study. International Journal of Sports Medicine 23:1-9, 2002.
  3. Green JS, Stanforth PR, Gagnon J, Leon AS, Rao DC, Skinner JS, Bouchard C, Rankinen T and Wilmore JH. Menopause, estrogen, and training effects on exercise hemodynamics:  The HERITAGE Family Study. Medicine and Science in Sports and Exercise 34:74-82, 2002.
  4. Couillard C, Mauriege P, Prud’homme D, Nadeau A, Tremblay A, Bouchard C, and Despres J-P. Plasma leptin response to an epinephrine infusion in lean and obese women.  Obes Res, 10(1):6-13, 2002
  5. Lanouette C-M, Chagnon YC, Rice T, Perusse L, Muzzin P, Giacobino JP, Gagnon J, Wilmore JH, Leon AS, Skinner JS, Rao DC and Bouchard C. Uncoupling protein 3 gene is associated with body composition changes with training in HERITAGE study. Journal of Applied Physiology 92:1111-1118, 2002.
  6. Tanaka S, Togashi K, Rankinen T, Perusse L, Leon AS, Rao DC, Skinner JS, Wilmore JH, Bouchard C. Is adiposity at normal body weight relevant for cardiovascular disease risk? International Journal of Obesity 26:176-183, 2002
  7. Garenc C, Pérusse L, Chagnon YC, Rankinen T, Gagnon J, Borecki IB, Leon AS, Skinner JS, Wilmore JH, Rao DC and Bouchard C. The hormone-sensitive lipase gene and body composition: The HERITAGE Family Study. International Journal of Obesity 26:220-227, 2002.
  8. Rice T, Chagnon YC, Pérusse L, Borecki IB, Ukkola O, Rankinen T, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Bouchard C, Rao DC. A genome-wide linkage scan for abdominal subcutaneous and visceral fat in black and white families: the HERITAGE Family Study. Diabetes 51:848-855, 2002
  9. Heo M, Leibel RL, Fontaine KR, Boyer BB, Chung WK, Koulu M, Karvonen MK, Pesonen U, Rissanen A, Laasko M, Uusitupa MIJ, Chagnon Y, Bouchard C, Donohoue PA, Burns TL, Shuldiner AR, Silver K, Andersen RE, Pedersen O, Schwald S, Sorensen TIA, Behn P, Permutt MA, Jacobs KB, Elston RC, Hoffman DJ, Gropp E and Allison DB.  A meta-analytic investigation of linkage and association of common leptin receptor (LEPR) polymorphisms with body mass index and waist circumference. Int J Obes 26:640-6, 2002.
  10. Rankinen T, Rice T, Leon AS, Skinner JS, Wilmore JH, Rao DC and Bouchard C. G protein b3 polymorphism and hemodynamic and body composition phenotypes in the HERITAGE Family Study. Physiological Genomics 8:151-157, 2002
  11. Feitosa MF, Rice T, Rosmond R, Borecki IB, An P, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Bouchard C and Rao DC. A genetic study of cortisol measured before and after endurance training: The HERITAGE Family Study. Metabolism 51: 360-365, 2002
  12. Rice T, Despres JP, Perusse L, Hong Y, Province MA, Bergeron J, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Bouchard C, Rao DC. Familial aggregation of blood lipid response to exercise training in the health, risk factors, exercise training and genetics (HERITAGE) Family Study. Circulation 105:1904-1908, 2002.
  13. Ukkola O, Tremblay A and Bouchard C. Lipoprotein lipase polymorphisms and responses to long-term overfeeding. J Intern Med 251: 429-436, 2002.
  14. Rice T, Chagnon YC, Borecki IB, Pérusse L, Collier G, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Bouchard C and Rao DC. Familial resemblance for plasma leptin: sample homogeneity across adiposity and ethnic groups. Obesity Research 10:351-360, 2002
  15. Rankinen T, Perusse L, Weisnagel SJ, Snyder EE, Chagnon YC, Bouchard C. The human obesity gene map: The 2001 update. Obes Res 10:196-243, 2002
  16. Sun G, Ukkola O, Rankinen T, Joanisse DR, Bouchard C. Skeletal muscle characteristics predict body fat gain in response to overfeeding in never-obese young men. Metabolism 51:451-456, 2002
  17. Wauters M, Considine RV, Chagnon M, Mertens I, Rankinen T, Bouchard C, Van Gaal LF. Leptin levels, leptin receptor gene polymorphisms and energy metabolism in women. Obes Res 10;394-400, 2002
  18. Hunt MS, Katzmarzyk PT, Perusse L, Rice T, Rao DC, and Bouchard C. Familial resemblance of 7-year changes in body mass and adiposity. Obes Res 10:507-517, 2002
  19. Jackson AS, Stanforth PR, Gagnon J, Rankinen T, Leon AS, Rao DC, Skinner JS, Bouchard C, Wilmore JH. The effect of sex, age, and race on estimating percent body fat from body mass index: The HERITAGE Family Study. International Journal of Obesity 26:789-796, 2002
  20. Rosmond R, Bouchard C and Bjorntorp P. Allelic variants in the GABAaα6 receptor subunit gene (GABRA6) is associated with abdominal obesity and cortisol secretion.  Int J Obes 26: 938-941, 2002.
  21. Rosmond R, Bouchard C and Bjorntorp P. 5-HT2A receptor gene promoter polymorphism in relation to abdominal obesity and cortisol. Obes Res 10:585-589, 2002.
  22. Rosmond R, Bouchard C and Bjorntorp P.  Lack of association between the uncoupling protein-2 Ala55Val gene polymorphism and phenotypic features of the Metabolic Syndrome. Biochimica et biophysica Acta 1588:103-105, 2002.
  23. Rosmond R, Chagnon M, Bouchard C and Bjorntorp P. Polymorphism in exon 4 of the human 3ß-hydroxysteroid dehydrogenase type I gene (HSD3B1) and blood pressure.  Biochem Biophys Res Commun 293:629-632, 2002.
  24. Rosmond R, Ukkola O, Bouchard C and Bjorntorp P.  Polymorphisms in Exon 3 of the proopiomelanocortin gene in relation to serum leptin, salivary cortisol and obesity in Swedish men.  Metabolism 51(5): 642-644, 2002
  25. Rice T, An P, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Bouchard C and Rao DC. Heritability of HR and BP response to endurance exercise training in the HERITAGE Family Study. Medicine and Science in Sports and Exercise 34;972-979, 2002.
  26. Rice T, Rankinen T, Chagnon YC, Province MA, Pérusse L, Leon AS, Skinner JS, Wilmore JH, Bouchard C, Rao DC. Genomewide linkage scan for resting blood pressure: the HERITAGE Family Study. Hypertension 39:1037-1043, 2002
  27. Togashi K, Masuda H, Rankinen T, Tanaka S, Kamiya H, Bouchard C. A 12-year follow-up of treated obese children in Japan. Int J Obes 26:770-777, 2002
  28. Rankinen T, Bouchard C. Genetics and blood pressure response to exercise, and its interactions with adiposity. Prev Cardiol 2002:5;138-44.
  29. Simonen RL, Perusse L, Rankinen T, Rice T, Rao DC, Bouchard C. Familial aggregation of physical activity levels in the Quebec Family Study. Med Sci Sports Exerc 2002;34:1137-1142
  30. Garenc C, Perusse L, Chagnon YC, Rankinen T, Gagnon J, Borecki IB, Leon AS, Skinner JS, Wilmore JH, Rao DC, Bouchard C. The alpha2 –adrenergic receptor gene and body fat content and distribution: The HERITAGE Family Study. Molecular Medicine 8: 88-94, 2002
  31. Ukkola O, Rankinen T, Gagnon J, Leon AS, Skinner JS, Wilmore JF, Rao DC, Bouchard C. A genome-wide linkage scan for steroids and SHBG levels in Black and White families: The HERITAGE Family Study. Journal of Clinical Endocrinology and Metabolism 87: 3708-3720, 2002
  32. Rankinen T, Perusse L, Rauramaa R, Rivera MA, Wolfarth B, Bouchard C. The human gene map for performance and health-related fitness phenotypes: the 2001 update. Med Sci Sports Exerc 2002;34:1219-1233
  33. Rankinen T, An P, Pérusse L, Rice T, Chagnon YC, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Rao DC and Bouchard C. Genome-wide linkage scan for exercise stroke volume and cardiac output in the HERITAGE Family Study. Physiological Genomics 10; 57-62, 2002.
  34. Katzmarzyk P, Craig CL and Bouchard C.  Adiposity, adipose tissue distribution and mortality rates in the Canada Fitness Survey follow-up study. Int J Obes Relat Metab Disord 26:1054-1059, 2002.
  35. Ukkola O, Ravussin E, Jacobson P, Pérusse L, Rankinen T, Tschöp M, Heiman ML, Leon AS, Rao DC, Skinner JS, Wilmore JH, Sjöstrom L and Bouchard C. Role of ghrelin polymorphisms in obesity based on three different studies. Obesity Research 10; 782-791, 2002
  36. Feitosa MF, Gaskill SE, Rice T, Rankinen T, Bouchard C, Rao DC, Wilmore JH, Skinner JS, Leon AS. Major gene effects on exercise ventilatory threshold: the HERITAGE Family Study. Journal of Applied Physiology 93;1000-1006, 2002
  37. Boucher N, Lanouette CM, Larose M, Perusse L, Bouchard C, and Chagnon YC. A +2138InsCAGACC polymorphism of the melanocortin receptor 3 gene is associated in human with fat level and partitioning in interaction with body corpulence.  Molec Med 8(3): 158-165, 2002.
  38. Argyropoulos G, Rankinen T, Neufeld DR, Rice T, Province MA, Leon AS, Skinner JS, Wilmore JH, Rao DC, Bouchard C. A polymorphism in the human agouti-related protein is associated with late-onset obesity. Journal of Clinical Endocrinology and Metabolism 87;4198-4202, 2002
  39. Fortier MD, Katzmarzyk PT and Bouchard C. Physical activity, aerobic fitness, and seven-year changes in adiposity in the Canadian population. Can J Appl Physiol 27(5): 449-462, 2002.
  40. Jacobson P, Ukkola O, Rankinen T, Snyder EE, Leon AS, Rao DC, Skinner JS, Wilmore JH, Lonn L, Cowan Jr GS, Sjostrom L, Bouchard C. Melanocortin 4 receptor sequence variations are seldom a cause of human obesity: The Swedish Obese Subjects, the HERITAGE Family Study and a Memphis Cohort. Journal of Clinical Endocrinology and Metabolism 87: 4442-4446, 2002
  41. Feitosa MF, Rice T, Rosmond R, Rankinen T, Leon AS, Skinner JS, Wilmore JH, Bouchard C, Rao DC. Pleiotropic relationships between cortisol levels and adiposity: The HERITAGE Family Study. Obesity Research 10:1222-1231, 2002
  42. Rauramaa R, Kuhanen R, Lakka TA, Vaisanen SB, Halonen P, Alen M, Rankinen T and Bouchard C.  Physical exercise and blood pressure with reference to the angiotensinogen M235T polymorphism.  Physiol Genom 10: 71-77, 2002.
  43. Rosmond R, Bouchard C and Bjorntrop P. A C-1291G polymorphism in the a2A-adrenergic receptor gene (ADRA2A) promoter is associated with cortisol escape from dexamethasone and elevated glucose levels.  J Intern Med 251:252-257, 2002.
  44. VanRossum CTM, Hoebee B, Seidell JC, Bouchard C, vanBaak MA, deGroot CPGM, Chagnon M, deGraaf C and Saris WHM.  Genetic factors as predictors of weight gain in young adult Dutch men and women. Int J Obes 26:640-6, 2002

2003

  1. Feitosa MF, Borecki I, Rankinen T, Leon AS, Skinner JS, Wilmore JH, Bouchard C and Rao DC. Lack of pleiotropic effects between adiposity and sex hormone-binding globulin levels before and after 20 weeks of exercise training: the HERITAGE Family Study. Metabolism 52:35-41, 2003.
  2. An P, Perusse L, Rankinen T, Borecki IB, Gagnon J, Leon AS, Skinner JH, Wilmore JH, Bouchard C and Rao DC. Familial aggregation of exercise heart rate and blood pressure in response to 20 weeks of endurance training: The HERITAGE Family Study. International Journal of Sports Medicine 24:57-62, 2003
  3. Weltman A, Despres JP, Clasey JL, Weltman JY, Wideman L, Kanaley J, Patrie J, Bergeron J, Thorner MO, Bouchard C and Hartman, ML. Impact of abdominal visceral fat, growth hormone, fitness, and insulin on lipids and lipoproteins in older adults.  Metabolism, 52: 73-80, 2003
  4. Argyropoulos G, Rankinen T, Bai F, Rice T, Province MA, Leon AS, Skinner JS, Wilmore JH, Rao DC, Bouchard C. The Agouti Related Protein and Body Fatness in Humans. International Journal of Obesity 27:276-280, 2003
  5. Chagnon YC, Rankinen T, Snyder EE, Weisnagel SJ, Perusse L, Bouchard C. The human obesity gene map: the 2002 update. Obesity Research 2003;11:313-367
  6. An P, Hong Y, Weisnagel JS, Rice T, Rankinen T, Leon AS, Skinner JS, Wilmore JH, Chagnon YC, Bergman RN, Bouchard C and Rao DC. Genomic scan of glucose and insulin metabolism phenotypes: The HERITAGE Family Study. Metabolism 52:246-53, 2003.
  7. Rosmond R, Chagnon M and Bouchard C.  The Pro12Ala PPARy2 gene missense mutation is associated with obesity and insulin resistance in Swedish middle-aged men. Diabetes Metab Res Rev 19: 159-163, 2003.
  8. Allison DB, Miller RA, Austad SN, Bouchard C, Leibel R, Klebanov S, Johnson T, and Harrison DE. Genetic variability in response to caloric restriction in animals and in regulation of metabolism and obesity in humans. J Gerontol 56A: 55-65, 2001.
  9. Boule NG, Tremblay A, Gonzalez-Barranco J, Aguilar-Salinas CA, Lopez-Alvarenga JC, Despres JP, Bouchard C, Gomez-Perez FJ, Castillo-Martinez L and Rios-Torres JM.  Insulin resistance and abdominal adiposity in young men with documented malnutrition during the first year of life.  Int J Obes 27: 598-604, 2003.
  10. Ukkola O, Joanisse DR, Tremblay A and Bouchard C.  Na+ -K+ -ATPase α2-gene and skeletal muscle characteristics in response to long-term overfeeding.  J Appl Physiol 94: 1870-1874, 2003.
  11. Ukkola O, Rankinen T, Rice T, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Rao DC and Bouchard C. Interactions among the b2- and b3-adrenergic receptor genes and total body fat and abdominal fat level in the HERITAGE Family Study. International Journal of Obesity 27:389-393, 2003.
  12. Perusse L, Rankinen T, Rauramaa R, Rivera M, Wolfarth B, Bouchard C. The human gene map for performance and health-related fitness phenotypes: the 2002 update. Med Sci Sports Exerc 2003;35:1248-64.
  13. Simonen RL, Rankinen T, Perusse L, Rice T, Rao DC, Chagnon YC, Bouchard C. Genome-wide linkage scan for physical activity levels in the Quebec Family Study. Medicine and Science in Sports and Exercise 2003;35:1355-9
  14. Imbeault P, Prins JB, Stolic J, Russell AW, O’Moore-Sullivan T, Despres J-P, Bouchard C and Tremblay A. Aging per se does not influence glucose homeostasis.  Diabetes Care 26:480-484, 2003.
  15. Garenc C, Pérusse L, Chagnon YC, Rankinen T, Gagnon J, Borecki IB, Leon AS, Skinner JS, Wilmore JH, Rao DC and Bouchard C. Effects of beta-2-adrenergic receptor gene variants on adiposity: The HERITAGE Family Study. Obesity Research 11:612-618, 2003.
  16. Lakka TA, Rankinen T, Weisnagel SJ, Chagnon YC, Rice T, Leon AS, Skinner JS, Wilmore JH, Rao DC and Bouchard C. A Quantitative Trait Locus on 7q31 for the Changes in Plasma Insulin in Response to Exercise Training: the HERITAGE Family Study. Diabetes 52:1583-1587, 2003.
  17. Simonen RL, Rankinen T, Perusse L, Leon AS, Skinner JS, Wilmore JH, Rao DC, Bouchard C. A dopamine D2 receptor gene polymorphism and physical activity in two family studies. Physiology and Behavior 78:751-757, 2003.
  18. Jacqmain M, Doucet E, Despres J-P, Bouchard C and Tremblay A.  Calcium intake, body composition, and lipoprotein-lipid concentrations in adults.  Am J Clin Nutr 77:1448-1452, 2003.
  19. Katzmarzyk PT, Tremblay A, Perusse L, Despres J-P and Bouchard C.  The utility of the international child and adolescent overweight guidelines for predicting coronary heart disease risk factors.  J Clin Epidemiol 56: 456-462, 2003.
  20. Doucet E, Imbeault P, St-Pierre S, Almeras N, Mauriege P, Despres J-P, Bouchard C and Tremblay A.  Greater than predicted decrease in energy expenditure during exercise after body weight loss in obese men.  Clin Sci; 105: 89-98, 2003.
  21. Drapeau V, Provencher V, Lemieux, Despes J-P, Bouchard C and Tremblay A.  Do 6-y changes in eating behaviors predict changes in body weight?  Results from the Quebec Family Study. Int J Obes 27: 808-814, 2003.
  22. Rico-Sanz J, Rankinen T, Joanisse D, Leon AS, Skinner JS, Wilmore JH, Rao DC and Bouchard C. Associations between cardiorespiratory responses to exercise and the C34T AMPD1 gene polymorphism in the HERITAGE Family Study. Physiol Genom 14:161-166, 2003.
  23. Bosse Y, Perusse L, Despres J-P, Lamarche B, Chagnon YC, Rice T, Rao DC, Bouchard C and Vohl M-C.  Evidence for a major quantitative trait locus on chromosome 17q21 affecting low-density lipoprotein peak particle diameter. Circulation 107: 2361-2368, 2003.
  24. Rankinen T, Rice T, Boudreau A, Leon AS, Skinner JS, Wilmore JH, Rao DC and Bouchard C.  Titin is a candidate gene for stroke volume response to endurance training:  the HERITAGE Family Study. Physiological Genomics 15;27-33, 2003.
  25. Tremblay A, Bouchard L, Bouchard C, Despres J-P, Drapeau V and Perusse L.  Long-term adiposity changes are related to a glucocorticoid receptor polymorphism in young females.  J Clin Endocrinol Metab 88: 3141-3145, 2003.
  26. Eisenmann JC, Katzmarzyk PT, Perusse L, Bouchard C and Malina RM. Estimated daily energy expenditure and blood lipids in adolescents: The Quebec Family Study.  J Adoles Health 33:147-153, 2003.
  27. Rico-Sanz J, Rankinen T, Joanisse D, Leon AS, Skinner JS, Wilmore JH, Rao DC and Bouchard C. Familial resemblance of muscle phenotypes in the sedentary state and their responses to training: the HERITAGE Family Study.  Medicine and Science in Sports and Exercise 35:1360-1366, 2003.
  28. An P, Borecki IB, Rankinen T, Perusse L, Leon AS, Skinner JS, Wilmore JH, Bouchard C, Rao DC. Evidence of major gene for exercise heart rate and blood pressure at baseline and in response to 20 weeks of endurance training: The HERITAGE Family Study. International Journal of Sports Medicine 24;492-498, 2003.
  29. Rosmond R, Chagnon M, Bouchard C and Bjorntorp P.  Increased abdominal obesity, insulin and glucose levels in nondiabetic subjects with a T29C polymorphism of the transforming growth factor-β1 gene. Horm Res 59: 191-194, 2003.
  30. Katzmarzyk PT, Leon AS, Wilmore JH, Skinner JS, Rao DC, Rankinen T and Bouchard C. Targeting the metabolic syndrome with exercise: Evidence from the HERITAGE Family Study. Medicine and Science in Sports and Exercise 35;1703-1709, 2003
  31. Skinner JS, Gaskill SE, Rankinen T, Leon AS, Rao DC, Wilmore JH and Bouchard C. Heart rate vs. VO2 max:  Age, Sex, Race, Initial Fitness and Training Response- HERITAGE.  Medicine and Science in Sports and Exercise 35:1908-1913, 2003.
  32. Couillard C, Bergeron J, Després JP, Gagnon J, Rankinen T, Leon AS, Rao DC, Skinner JS, Wilmore JH and Bouchard C. Apolipoprotein AI and AI:AII containing lipoproteins in white men and women of the HERITAGE Family Study: Associations with metabolic risk profile variables. Metabolism 52:1530-1536, 2003
  33. Bosse Y, Despres J-P, Bouchard C, Perusse L and Vohl M-C.  The peroxisome proliferator-activated receptor α L162V mutation is associated with reduced adiposity.  Obes Res 11:809-816, 2003.
  34. Desmeules A, Couillard C, Tchernof A, Bergeron J, Rankinen T, Leon AS, Rao DC, Skinner JS, Wilmore JH, Després J-P and Bouchard C. Post-heparin lipolytic enzyme activities, sex hormones and sex hormone-binding globulin (SHBG) in men and women: the HERITAGE Family Study. Atherosclerosis 171:343-350, 2003
  35. Loos R, Katzmarzyk P, Rao DC, Rice T, Leon AS, Wilmore JH, Skinner JS, Rankinen T, Bouchard C.  Genome-wide linkage scan for metabolic syndrome in the HERITAGE Family Study. Journal of Clinical Endocrinology and Metabolism 88:5935-5943, 2003
  36. Ukkola O, Chagnon M, Tremblay and Bouchard C.  Genetic variation at the adipsin locus and response to long-term overfeeding.  Eur J Clin Nutr 57:1073-1078, 2003.
  37. Ukkola O, Ravusssin E, Jacobson P, Sjostrom L and Bouchard C.  Mutations in the adiponectin gene in lean and obese subjects from the Swedish Obese Subjects cohort.  Metabolism, 52(7): 881-884, 2003.
  38. Perusse L and Bouchard C. Bases genetiques de l’obesite familiale au Quebec.  Medecine/Sciences 19:937-42, 2003.
  39. Loos RJF and Bouchard C.  Obesity – is it a genetic disorder?  J Intern Med 254: 401-425, 2003
  40. Bosse Y, Vohl M-C, Despres J-P, Lamarche B, Rice T, Rao DC, Bouchard C and Perusse L. Heritability of LDL peak particle diameter in the Quebec Family Study. Genet Epidemiol 25:375-381, 2003.
  41. Paradis M-E, Couture P, Bosse Y, Despres J-P, Perussse L, Bouchard C, Vohl M-C, and Lamarche B. The T111l mutation in the EL gene modulates the impact of dietary fat on the HDL profile in women.  J Lipid Res 44: 1902-1908, 2003.

2004

  1. Leon AS, Togashi K, Rankinen T, Despres JP, Rao DC, Skinner J, Wilmore J and Bouchard C. Association of apolipoprotein E polymorphism with blood lipids and maximal oxygen uptake in the sedentary state and after exercise training in the HERITAGE Family Study. Metabolism 53:108-116, 2004
  2. Rankinen T, Tiwari H. Genome scans for human nutritional traits. What have we learned? Nutrition 2004;20:9-13.
  3. Lakka H-M, Tremblay A, Despres J-P, and Bouchard C.  Effects of long-term negative energy balance with exercise on plasma lipid and lipoprotein levels in identical twins.  Atherosclerosis 172: 127-133, 2004.
  4. Rico-Sanz J, Rankinen T, Rice T, Leon AS, Skinner JS, Wilmore JH, Rao DC and Bouchard C. Quantitative trait loci for maximal exercise capacity phenotypes and their responses to training in the HERITAGE Family Study. Physiological Genomics 16;256-260, 2004
  5. Shephard RJ, Rankinen T, Bouchard C. Test-retest errors and the apparent heterogeneity of training response. European Journal of Applied Physiology 2004;91:199-203.
  6. Tanaka S, Togashi K, Rankinen T, Perusse L, Leon AS, Rao DC, Skinner JS, Wilmore JH, Despres JP, Bouchard C. Sex differences in the relationships of abdominal fat to cardiovascular disease risk among normal-weight white subjects. International Journal of Obesity 28;320-323, 2004
  7. Ukkola O, Bouchard C. Role of candidate genes in the responses to long-term overfeeding: review of findings.  Obes Rev 5:3-12; 2004
  8. Snyder EE, Walts B, Perusse L, Chagnon YC, Weisnagel SJ, Rankinen T, Bouchard C. The human obesity gene map: the 2003 update. Obesity Research 2004;12:369-439
  9. Ukkola O, Kesaniemi YA, Tremblay A and Bouchard C.  Two variants in the resistin gene and the response to long-term overfeeding.  Eur J Clin Nutr 58: 654-659, 2004.
  10. Janssen I, Katzmarzyk PT, Ross R, Leon AS, Skinner JS, Rao DC, Wilmore JH, Rankinen T and Bouchard C. Fitness alters the association of BMI and waist circumference with total and abdominal fat. Obesity Research 12;525-537, 2004.
  11. Gonzalez-Barranco J, Rios-Torres JM, Castillo-Martinez L, Lopez-Alvarenga JC, Aguilar-Salinas CA, Bouchard C, Despres J-P and Tremblay A. Effect of malnutrition during the first year of life on adult plasma insulin and glucose tolerance. Metabolism 52: 1005-1011, 2003
  12. Teran-Garcia M, Despres J-P, Couillard C, Tremblay A and Bouchard C.  Effects of long-term overfeeding on plasma lipoprotein levels in identical twins.  Atherosclerosis 173: 277-283, 2004.
  13. Konig D, Vaisanen SB, Bouchard C, Halle M, Lakka TA, Baumstark MW, Alen M, Berg A, and Rauramaa R.  Cardiorespiratory fitness modifies the association between dietary fat intake and plasma fatty acids.  Eur J Clin Nutr 57: 810-815; 2004.
  14. Collaku A, Rankinen T, Rice T, Leon AS, Rao DC, Skinner JS, Wilmore JH and Bouchard C. Genome-wide linkage scan for dietary energy and energy nutrient intakes: The Health, Risk Factors, Exercise Training, and Genetics (HERITAGE) Family Study. American Journal of Clinical Nutrition 79:881-886, 2004.
  15. Bosse Y, Chagnon YC, Despres J-P, Rice T, Rao DC, Bouchard C, Perusse L and Vohl M-C. Genome-wide linkage scan reveals multiple susceptibility loci influencing lipid and lipoprotein levels in the Quebec Family Study.  J Lipid Res 45: 419-426, 2004
  16. Bai F, Rankinen T, Charbonneau C, Belsham DD, Rao DC, Bouchard C, Argyropoulos G. Functional dimorphism of two hAGRP promoter SNPs in linkage disequilibrium. Journal of Medical Genetics 2004;41:350-353
  17. Sklan EH, Lowenthal A, Korner M, Ritov Y, Landers DM, Rankinen T, Bouchard C, Leon AS, Rice T, Rao DC, Wilmore JH, Skinner JS and Soreq H.  Acetylcholinesterase/paraoxonase genotype and expression predict anxiety scores in Health, Risk Factors, Exercise Training, and Genetics Study. Proc Natl Acad Sci 101:5512-5517, 2004.
  18. Alfonzo-Gonzalez G, Doucet E, Almeras N, Bouchard C and Tremblay A.  Estimation of daily energy needs with the FAO/WHO/UNU 1985 procedures in adults: comparison to whole-body indirect calorimetry measurements.  Eur J Clin Nutr  58:1125-31, 2004.
  19. Provencher V, Drapeau V, Tremblay A, Despres J-P, Bouchard C and Lemieux S.  Eating behaviors, dietary profile and body composition according to dieting history in men and women of the Quebec Family Study.  Br J Nutr 91: 997-1004, 2004
  20. Lakka TA, Rankinen T, Weisnagel SJ, Chagnon YC, Lakka HM, Ukkola O, Boule N, Rice T, Leon AS, Skinner JS, Wilmore JH, Rao DC, Bergman R, Bouchard C. Leptin and leptin receptor gene polymorphisms and changes in glucose homeostasis in response to regular exercise in nondiabetic individuals: The HERITAGE Family Study. Diabetes 53:1603-1608, 2004
  21. Rankinen T, Perusse L, Rauramaa R, Rivera MA, Wolfarth B, Bouchard C. The human gene map for performance and health-related fitness phenotypes: the 2003 update. Med Sci Sports Exerc 2004;36:1451-1469.
  22. Stanforth P, Jackson AS, Green JS, Gagnon J, Rankinen T, Despres J-P, Bouchard C, Leon AS, Rao DC, Skinner JS and Wilmore JH. Generalized abdominal visceral fat prediction models for black and white adults aged 17-65 y: The HERITAGE Family Study. International Journal of Obesity 28:925-932, 2004.
  23. Katzmarzyk PT, Srinivasan SR, Chen W, Malina RM, Bouchard C, and Berenson GS. Body mass index, waist circumference, and clustering of cardiovascular disease risk factors in biracial sample of children and adolescents. Pediatrics 114 (2): e198-e205, 2004.
  24. Rauramaa R, Halonen P, Vaisanen SB, Lakka TA, Schmidt-Trucksass A, Berg A, Penttila IM, Rankinen T and Bouchard C.  Effects of aerobic physical exercise on inflammation and atherosclerosis in men: The DNASCO Study.  Ann Intern Med 140: 1007-1014, 2004.
  25. Koivukoski L, Fisher SA, Kanninen T, Lewis CM, Von Wowern F, Hunt S, Kardia SL, Levy D, Perola M, Rankinen T, Rao DC, Rice T, Thiel BA, Melander O. Meta-analysis of genome-wide scans for hypertension and blood pressure in Caucasians shows evidence of susceptibility regions on chromosomes 2 and 3. Hum Mol Genet 2004;13:2325-2332.
  26. Tremblay A, Perusse L, Bouchard C.  Energy balance and body-weight stability: impact of gene-environment interactions.  Br J Nutr. 92: S63-S66, 2004
  27. Thomis MA, Huygens W, Heuninckx S, Chagnon M, Maes HHM, Claessens AL, Vlietinck R, Bouchard C, Beunen GP. Exploration of myostatin polymorphisms and the angiotensin-converting enzyme insertion/deletion genotype in responses of human muscle to strength training.  Eur J Appl Physiol, 92: 267-274, 2004.
  28. Bosse Y, Chagnon YS, Despres J-P, Rice T, Rao DC, Bouchard C, Perusse L, and Vohl M-C.  Compendium of genome-wide scans of lipid-related phenotypes: adding a new genome-wide search of apolipoprotein levels. J Lipid Res  45: 2174-2184, 2004.
  29. Loos RJF, Rankinen T, Leon AS, Skinner JS, Wilmore JH, Rao DC and Bouchard C. Calcium intake is associated with adiposity in black and white men and white women of the HERITAGE Family Study. Journal of Nutrition 134:1772-1778, 2004.
  30. Drapeau V, Despres J-P, Bouchard C, Allard L, Fournier G, Leblanc C and Tremblay A.  Modifications in food-group consumption are related to long-term body-weight changes.  Am J Clin Nutr 80:29-37, 2004.
  31. Sjostrom L, Lindroos A-K, Peltonen M, Torgerson J, Bouchard C, Carlsson B, Dahlgren S, Larsson B, Narbro K, Sjostrom CD, Sullivan M, and Wedel H.  Lifestyle, diabetes, and cardiovascular risk factors 10 years after bariatric surgery.  N Engl J Med 351: 2683-2693, 2004.
  32. Green JS, Stanforth PR, Rankinen T, Leon AS, Rao DC, Skinner JS, Bouchard C, Wilmore JH. The effects of exercise training on abdominal visceral fat, body composition, and indicators of the metabolic syndrome in postmenopausal women with and without estrogen replacement therapy: The HERITAGE Family Study. Metabolism 53:1192-1196, 2004.
  33. Ardern CI, Katzmarzyk PT, Janssen I, Leon AS, Wilmore JH, Skinner JS, Rao DC, Rankinen T, Despres JP, Rankinen T, Bouchard C. Race and sex similarities in exercise-induced changes in blood lipids and fatness. Medicine and Science in Sports and Exercise 36:1610-1615, 2004.
  34. Bouchard L, Weisnagel SJ, Engert JC, Hudson TJ, Bouchard C, Vohl M-C, and Perusse L.  Human resistin gene polymorphism is associated with visceral obesity and fasting and oral glucose stimulated C-peptide in the Quebec Family Study.  J Endocrinol Invest 27: 1003-1009, 2004.

2005

  1. Boulé NG, Weisnagel SJ, Lakka TA, Tremblay A, Bergman RN, Rankinen T, Leon AS, Skinner JS, Wilmore JH, Rao DC, Bouchard C. Effects of exercise training on glucose homeostasis: The HERITAGE Family Study. Diabetes Care 28:108-114, 2005.
  2. Feitosa MF, Borecki IB, Rankinen T, Rice T, Despres JP, Chagnon YC, Gagnon J, Leon AS, Skinner JS, Bouchard C, Province MA, Rao DC. Evidence of QTLs on chromosomes 1q42 and 8q24 for LDL-cholesterol and apoB levels in the HERITAGE Family Study. Journal of Lipid Research 46:281-286, 2005
  3. Bouchard L, Mauriege P, Vohl MC, Bouchard C, Perusse L. Plasminogen-activator inhibitor-1 polymorphisms are associated with obesity and fat distribution in the Quebec Family Study: evidence of interactions with menopause. Menopause 12(2):136-43, 2005.
  4. Loos RJF, Rankinen T, Perusse L, Tremblay A, Bouchard C. The melanocortin 4 receptor gene and physical activity in the Quebec Family Study. International Journal of Obesity 2005;29: 420-428.
  5. Perusse L, Rankinen T, Zuberi A, Chagnon YC, Weisnagel SJ, Argyropoulos G, Walts B, Snyder EE, Bouchard C. The human obesity gene map: the 2004 update. Obesity Research 2005;13:381-490
  6. Loos RJF, Rankinen T. Gene-diet interactions on body weight changes. J Am Diet Assoc 2005;105:29-34.
  7. Feitosa MF, Rice T, Rankinen T, Almasy L, Leon AS, Skinner JS, Wilmore JH, Bouchard C and Rao DC. Common genetic and environmental effects on lipid phenotypes: The HERITAGE Family Study. Human Heredity 59:34-40, 2005.
  8. Teran-Garcia M, Rankinen T, Koza RA, Rao DC, Bouchard C. Endurance training –induced changes in insulin sensitivity and gene expression. American Journal of Physiology – Endocrinology and Metabolism 288:E1168-78, 2005.
  9. Ukkola O, Rankinen T, Lakka T, Leon AS, Skinner JS, Wilmore JH, Rao DC, Kesaniemi YA, Bouchard C. Protein tyrosine phosphatase 1B variant associated with fat distribution and insulin metabolism. Obesity Research 13:829-834, 2005.
  10. Ukkola O, Santaniemi M, Rankinen T, Leon AS, Skinner JS, Wilmore JH, Rao DC, Bergman R, Kesaniemi YA, Bouchard C. Adiponectin polymorphisms, adiposity and insulin metabolism: HERITAGE Family Study and Oulu Diabetic Study. Ann Med 37:141-150, 2005.
  11. Bosse Y, Feitosa MF, Despres JP, Lamarche B, Rice T, Rao DC, Bouchard C, Perusse L, Vohl MC.  Detection of a major gene effect for LDL peak particle diameter and association with apolipoprotein H gene haplotype.  Atherosclerosis 182: 231-9, 2005.
  12. Wolfarth B, Bray MS, Hagberg JM, Perusse L, Rauramaa R, Rivera MA, Roth SM, Rankinen T, Bouchard C. The Human Gene Map For Performance and Health-Related Fitness Phenotypes: the 2004 Update. Med Sci Sports Exerc 2005;37:881-903.
  13. An P, Teran-Garcia M, Rice T, Rankinen T, Weisnagel SJ, Bergman RN, Boston RC, Mandel S, Stefanovski D, Leon AS, Skinner JS, Rao DC, Bouchard C. Genome-wide linkage scans for prediabetes phenotypes in response to 20 weeks of endurance exercise training in non-diabetic Whites and Blacks: The HERITAGE Family Study. Diabetologia 48:1142-1149, 2005.
  14. Teran-Garcia M, Santoro N, Rankinen T, Bergeron J, Rice T, Leon AS, Rao DC, Skinner JS, Bergman RN, Despres JP, Bouchard C. Hepatic lipase gene variant –514C>T is associated with lipoprotein and insulin sensitivity response to regular exercise: the HERITAGE Family Study. Diabetes 54;2251-2255, 2005.
  15. An P, Borecki IB, Rankinen T, Despres JP, Leon AS, Skinner JS, Wilmore JH, Bouchard C and Rao DC. Evidence of major genes for plasma HDL, LDL cholesterol and triglyceride levels at baseline and in response to 20 weeks of endurance training: the HERITAGE Family Study. Int J Sports Med 26;414-419, 2005 
  16. Feitosa MF, Rice T, Rankinen T, Province MA, Chagnon YC, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Despres JP, Bouchard C, Rao DC, Borecki IB. Evidence of QTLs on chromosomes 13q and 14q for triglycerides before and after 20 weeks of exercise training: The HERITAGE Family Study. Atherosclerosis 182;349-360, 2005.
  17. Bouchard C.  Gene-Physical Activity Interactions and the Cardiovascular Disease Risk Profile. Jpn Heart J 45: S94-S101, 2005  
  18. Eisenmann JC, Katzmarzyk PT, Perusse L, Tremblay A, Despres J-P, Bouchard C. Aerobic fitness, body mass index, and CVD risk factors among adolescents: the Quebec family study. Int J Obes 29: 1077-83, 2005
  19. Boule NG, Bouchard C, Tremblay A. Physical fitness and the metabolic syndrome in adults from the Quebec Family Study. Can J Appl Physiol 30:140-56, 2005
  20. Janssen I, Katzmarzyk PT, Srinivasan SR, Chen W, Malina RM, Bouchard C, Berenson GS. Combined influence of body mass index and waist circumference on coronary artery disease risk factors among children and adolescents. Pediatrics 115: 1623-30, 2005
  21. Janssen I, Katzmarzyk PT, Srinivasan SR, Chen W, Malina RM, Bouchard C, Berenson GS. Utility of childhood BMI in the prediction of adulthood disease: comparison of national and international references. Obes Res 13: 1106-15, 2005
  22. Lakka TA, Lakka HM, Rankinen T, Leon AS, Rao DC, Skinner JS, Wilmore JH, Bouchard C. Effect of exercise training on plasma levels of C-reactive protein in healthy adults: the HERITAGE Family Study. European Heart Journal 26;2018-2025, 2005.
  23. Blouin K, Despres J-P, Couillard C, Tremblay A, Prud’homme D, Bouchard C, Tchernof A. Contribution of age and declining androgen levels to features of the metabolic syndrome in men. Metabolism 54:1034-40, 2005.
  24. Loos RJF, Rankinen T, Rice T, Rao DC, Leon AS, Skinner JS, Wilmore JH, Argyropoulos G, Bouchard C. Two ethnic-specific polymorphisms in the Agouti-Related protein gene are associated with food intake in Whites and Blacks in the HERITAGE Family Study. American Journal of Clinical Nutrition 82:1097-101, 2005.
  25. Santoro N, Rankinen T, Perusse L, Loos RJ, Bouchard C. MC4R marker associated with stature in children and young adults: a longitudinal study. J Pediatr Endocrinol Metab 18: 859-63, 2005

  26. Malhotra A, Coon H, Feitosa MF, Li WD, North KE, Price RA, Bouchard C, Hunt SC, Wolford JK. Meta-analysis of genome-wide linkage studies for quantitative lipid traits in African Americans.  Hum Mol Genet 14(24): 3955-62, 2005.

2006

  1. An P, Rice T, Rankinen T, Leon AS, Skinner JS, Wilmore JH, Bouchard C, Rao DC. Genome-wide scan to identify quantitative trait loci for baseline resting heart rate and its response to endurance exercise training: The HERITAGE Family Study. International Journal of Sports Medicine 27:31-6, 2006